Last update
5/20/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***
Top Medical Research Studies
9
Omega-3s' mixed effects on heart health
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
8
Omega-3 reduces heart attack risk
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
8
We delved into how different types of fatty acids influence the risk of coronary heart disease (CHD) using data from a large study of over 89,000 adults.
Our findings revealed that omega-3 fatty acids seemed to lower the risk of CHD, standing out among other fatty acids. Interestingly, saturated and monounsaturated fats did show a positive link to CHD, but this was largely connected to their effect on triglyceride levels.
Overall, omega-3 fatty acids might offer a protective benefit against heart disease.
Our findings revealed that omega-3 fatty acids seemed to lower the risk of CHD, standing out among other fatty acids. Interestingly, saturated and monounsaturated fats did show a positive link to CHD, but this was largely connected to their effect on triglyceride levels.
Overall, omega-3 fatty acids might offer a protective benefit against heart disease.
Read More
Most Useful Reviews
9
Enhances heart function
Excellent! I take one capsule daily after meals. It lowers cholesterol, improves heart function and cleanses blood vessels. My hair condition has also improved.
Read More
7.5
Improves heart health
Excellent! Good Omega 3 for adults, lowers cholesterol, improves heart and brain health, hair and nervous system.
Read More
9
Best for heart health
1 people found this helpful
Omega is the most effective supplement I've found for heart health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
- All Researches
9
Omega-3s' mixed effects on heart health
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
9
We explored whether icosapent ethyl (IPE), a refined omega-3 fatty acid, could lower heart attack risk among cigarette smokers. In the REDUCE-IT trial, over 8,000 statin-treated patients were randomly assigned to receive either IPE or a placebo for nearly five years.
Our findings showed that IPE significantly reduced cardiovascular events by 25%, especially for current and former smokers. Participants using IPE experienced heart attack rates similar to non-smokers, suggesting that IPE may help lessen cardiovascular risks associated with smoking.
Our findings showed that IPE significantly reduced cardiovascular events by 25%, especially for current and former smokers. Participants using IPE experienced heart attack rates similar to non-smokers, suggesting that IPE may help lessen cardiovascular risks associated with smoking.
Read More
8
Omega-3 reduces heart attack risk
We investigated whether icosapent ethyl is beneficial in reducing heart attack rates among patients with well-managed low-density lipoprotein cholesterol (LDL-C).
Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.
Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.
Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
Read More
8
Omega-3 reduces heart attack risk
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
8
Omega-3 improves heart attack outcomes
We observed that icosapent ethyl, a type of omega-3 fish oil, plays a significant role in reducing heart attack risk among patients with atherosclerotic cardiovascular disease (ASCVD). In a study involving almost 5,800 participants, those taking icosapent ethyl experienced lower rates of major adverse cardiovascular events (MACE) compared to those on placebo.
The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Enhances heart function
Excellent! I take one capsule daily after meals. It lowers cholesterol, improves heart function and cleanses blood vessels. My hair condition has also improved.
Read More
7.5
Improves heart health
Excellent! Good Omega 3 for adults, lowers cholesterol, improves heart and brain health, hair and nervous system.
Read More
9
Best for heart health
1 people found this helpful
Omega is the most effective supplement I've found for heart health.
Read More
8
Strengthens heart health
Quality Omega 3 with clean ingredients. The large packaging is useful. It helps remove bad cholesterol and strengthens heart health. My hair appears shinier since I started taking it.
Read More
7
Benefits for heart
A great product at a decent price. Omega-3 is essential for dry skin, brittle nails, fatigue, and heart issues. Solgar has long been reputable, but this is the most affordable option I’ve found.
Read More
Frequently Asked Questions
9
Enhances heart function
Excellent! I take one capsule daily after meals. It lowers cholesterol, improves heart function and cleanses blood vessels. My hair condition has also improved.
8
Omega-3 reduces heart attack risk
We investigated whether icosapent ethyl is beneficial in reducing heart attack rates among patients with well-managed low-density lipoprotein cholesterol (LDL-C).
Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.
Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.
Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
8
Omega-3 improves heart attack outcomes
We observed that icosapent ethyl, a type of omega-3 fish oil, plays a significant role in reducing heart attack risk among patients with atherosclerotic cardiovascular disease (ASCVD). In a study involving almost 5,800 participants, those taking icosapent ethyl experienced lower rates of major adverse cardiovascular events (MACE) compared to those on placebo.
The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
8
Omega-3 reduces heart attack risk
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
8
We explored the effects of omega-3 fatty acids on preventing heart attacks through the VITamin D and OmegA-3 TriaL (VITAL), which involved nearly 26,000 adults. Participants received either omega-3 fish oil or an olive oil placebo for over five years.
Although the overall findings didn't show a significant reduction in major cardiovascular events, omega-3 supplementation did lower the risk of heart attacks and recurrent hospitalizations for heart failure. Interestingly, African Americans benefited the most from the treatment, showing substantial improvements in these areas.
More research is needed to identify which individuals might gain the most from omega-3 fish oil treatment.
Although the overall findings didn't show a significant reduction in major cardiovascular events, omega-3 supplementation did lower the risk of heart attacks and recurrent hospitalizations for heart failure. Interestingly, African Americans benefited the most from the treatment, showing substantial improvements in these areas.
More research is needed to identify which individuals might gain the most from omega-3 fish oil treatment.
9
Omega-3s' mixed effects on heart health
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
4
No overall benefit for heart attacks
We set out to explore if omega-3 fatty acids could help in reducing serious heart issues following a heart attack. In the OMEGA-REMODEL trial, patients were given either omega-3 supplements or a placebo for six months.
While the overall results showed no significant difference in major heart-related problems between those taking omega-3 and those not, we noticed that patients who responded well to the treatment—showing a rise in their omega-3 levels—had better long-term outcomes.
This suggests that, although omega-3 didn’t work for everyone, it could benefit those who have a strong response.
While the overall results showed no significant difference in major heart-related problems between those taking omega-3 and those not, we noticed that patients who responded well to the treatment—showing a rise in their omega-3 levels—had better long-term outcomes.
This suggests that, although omega-3 didn’t work for everyone, it could benefit those who have a strong response.
References
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
- Sun S, Hara A, Johnstone L, Hallmark B, Watkins JC, et al. Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation. Nutrients. 2024;16. 10.3390/nu16172933
- Ahmadi M, Askari VR, Shahri B, Mousavi Noghab SM, Jarahi L, et al. Omega-3 fatty acids effectively mitigate high-sensitivity C-reactive protein (hs-CRP) biomarker of inflammation in acute myocardial infarction patients: a randomized, double-blind, placebo-controlled clinical trial. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:881. 10.1007/s00210-024-03330-1
- Burger PM, Bhatt DL, Dorresteijn JAN, Koudstaal S, Mosterd A, et al. Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT. Eur Heart J Cardiovasc Pharmacother. 2024;10:488. 10.1093/ehjcvp/pvae030
- Bernhard B, Heydari B, Abdullah S, Francis SA, Lumish H, et al. Effect of six month's treatment with omega-3 acid ethyl esters on long-term outcomes after acute myocardial infarction: The OMEGA-REMODEL randomized clinical trial. Int J Cardiol. 2024;399:131698. 10.1016/j.ijcard.2023.131698
- Irfan A, Haider SH, Nasir A, Larik MO, Naz T. Assessing the Efficacy of Omega-3 Fatty Acids + Statins vs. Statins Only on Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of 40,991 Patients. Curr Probl Cardiol. 2024;49:102245. 10.1016/j.cpcardiol.2023.102245
- Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. 10.3390/nu15194235
- Jin D, Trichia E, Islam N, Lewington S, Lacey B. Associations of circulating fatty acids with incident coronary heart disease: a prospective study of 89,242 individuals in UK Biobank. BMC Cardiovasc Disord. 2023;23:365. 10.1186/s12872-023-03394-6
- Lyytinen AT, Yesmean M, Manninen S, Lankinen M, Bhalke M, et al. Fatty fish consumption reduces lipophilic index in erythrocyte membranes and serum phospholipids. Nutr Metab Cardiovasc Dis. 2023;33:1453. 10.1016/j.numecd.2023.04.011
- Chiusolo S, Bork CS, Gentile F, Lundbye-Christensen S, Harris WS, et al. Adipose tissue n-3/n-6 fatty acids ratios versus n-3 fatty acids fractions as predictors of myocardial infarction. Am Heart J. 2023;262:38. 10.1016/j.ahj.2023.03.019
- Kobara M, Shiraishi T, Noda K, Toba H, Nakata T. Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats. J Cardiovasc Transl Res. 2023;16:816. 10.1007/s12265-023-10363-z
- Rodriguez D, Lavie CJ, Elagizi A, Milani RV. Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health. Nutrients. 2022;14. 10.3390/nu14235146
- Bassuk SS, Manson JE. Marine omega-3 fatty acid supplementation and prevention of cardiovascular disease: update on the randomized trial evidence. Cardiovasc Res. 2023;119:1297. 10.1093/cvr/cvac172
- Nishizaki Y, Miyauchi K, Iwata H, Inoue T, Hirayama A, et al. Study protocol and baseline characteristics of Randomized trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, the combination of a randomized control trial and an observational biomarker study. Am Heart J. 2023;257:1. 10.1016/j.ahj.2022.11.008
- Miller M, Bhatt DL, Steg PG, Brinton EA, Jacobson TA, et al. Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking. Eur Heart J Cardiovasc Pharmacother. 2023;9:129. 10.1093/ehjcvp/pvac045
- Yokoyama Y, Kuno T, Morita SX, Slipczuk L, Takagi H, et al. Eicosapentaenoic Acid for Cardiovascular Events Reduction- Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. J Cardiol. 2022;80:416. 10.1016/j.jjcc.2022.07.008
